Activity of PLCe contributes to chemotaxis of fibroblasts towards PDGF
نویسندگان
چکیده
Marta Martins, Sean Warren, Christopher Kimberley, Anca Margineanu, Pascal Peschard, Afshan McCarthy, Maggie Yeo, Christopher J. Marshall, Christopher Dunsby, Paul M. W. French and Matilda Katan* Institute of Structural and Molecular Biology, Division of Biosciences, University College London, Gower Street, London WC1E 6BT, UK Department of Physics, Imperial College London, South Kensington, London SW7 2AZ, UK Division of Cancer Biology, Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK
منابع مشابه
Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGF.
Cell chemotaxis, such as migration of fibroblasts towards growth factors during development and wound healing, requires precise spatial coordination of signalling events. Phosphoinositides and signalling enzymes involved in their generation and hydrolysis have been implicated in regulation of chemotaxis; however, the role and importance of specific components remain poorly understood. Here, we ...
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